Does applying to a different university after getting an acceptance affect my visa negatively?

Yes, if you get an acceptance from one university, apply for your visa based on that acceptance, and then choose not to enroll there but instead apply to a different institution, it can negatively impact your visa process. Visa authorities might cancel your visa or reject future applications if they find out you didn't register at the university you declared. This situation can raise doubts about your true intentions during your visa application.